Биологическая активность
TSPO лиганд-1 is the лиганд of AUTAC4 that can be used in the synthesis of PROTACs. TSPO лиганд-1 is a mitochondrial outer membrane transmembrane structural domain protein can bind to AUTAC4 and regulate mitochondrial autophagy to promote targeted mitochondrial renewal. TSPO лиганд-1 is also involved in the transport of cholesterol from the outer to inner mitochondrial membrane and serves as a sensitive biomarker of brain injury and neurodegeneration.
Оригинал на английском
TSPO ligand-1 is the ligand of AUTAC4 that can be used in the synthesis of PROTACs. TSPO ligand-1 is a mitochondrial outer membrane transmembrane structural domain protein can bind to AUTAC4 and regulate mitochondrial autophagy to promote targeted mitochondrial renewal. TSPO ligand-1 is also involved in the transport of cholesterol from the outer to inner mitochondrial membrane and serves as a sensitive biomarker of brain injury and neurodegeneration.
Химические свойства
- CAS №
- 4560-08-1
- Брутто-формула
- C₁₆H₁₀ClNO₂
- Мол. масса
- 283.71 г/моль
- SMILES
- O=C(C(C1=C(C2=CC=CC=C2)NC3=C1C=CC=C3)=O)Cl
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.