Биологическая активность
Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor рецептор 2 (HER2) антитело-препарат conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 антитело, an enzymatically cleavable peptide-linker, and a topoisomerase I ингибитор. Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer.
Оригинал на английском
Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, and a topoisomerase I inhibitor. Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer.
Химические свойства
- CAS №
- 1826843-81-5 pH value: Corresponds to reference standard: PASS Non-reduced CE-SDS: >95% SEC-HPLC: >95% Isoelectric Point: Corresponds to reference standard Osmolality: Corresponds to reference standard: PASS Peptide mapping: Corresponds to reference standard: PASS N-terminal sequence: Corresponds to reference standard: PASS
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.