Биологическая активность
Toyaburgine is a unique isoquinoline compound that exhibits anti-tumor activity. It packs a punch by disrupting the PI3K/AKT/mTOR signaling pathway, causing significant morphological changes and клетка death in MIA PaCa-2 cells. On top of that, it puts the brakes on клетка migration and colony formation. This compound is showing a lot of promise in the realm of pancreatic cancer research.
Оригинал на английском
Toyaburgine is a unique isoquinoline compound that exhibits anti-tumor activity. It packs a punch by disrupting the PI3K/AKT/mTOR signaling pathway, causing significant morphological changes and cell death in MIA PaCa-2 cells. On top of that, it puts the brakes on cell migration and colony formation. This compound is showing a lot of promise in the realm of pancreatic cancer research.
Химические свойства
- Брутто-формула
- C₂₇H₂₅BrF₃NO₄
- Мол. масса
- 564.39 г/моль
- SMILES
- BrC(C=C1)=CC=C1C(C=C2)=CC=C2[N+]([C@@H](C)C3)=C(C)C4=C3C=C(OC)C=C4OC.O=C([O-])C(F)(F)F
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.