Биологическая активность
Talquetamab (JNJ-64407564) is a humanized bispecific антитело that binds to GPRC5D (member of G protein-coupled рецептор family C5 group D) and CD3 to induce T клетка-mediated killing of GPRC5D-expressing MM cells through T клетка recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity.
Оригинал на английском
Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity.
Химические свойства
- CAS №
- 2226212-40-2 pH value: Corresponds to reference standard: PASS Non-reduced CE-SDS: >95% SEC-HPLC: >95% Isoelectric Point: Corresponds to reference standard Osmolality: Corresponds to reference standard: PASS Peptide mapping: Corresponds to reference standard: PASS N-terminal sequence: Corresponds to reference standard: PASS
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.