Биологическая активность
SSR-180,575 is a препарат which acts as a селективный агонист at the peripheral benzodiazepine рецептор, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action.
Оригинал на английском
SSR-180,575 is a drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action.
Химические свойства
- CAS №
- 220448-02-2
- Брутто-формула
- C₂₁H₁₉N₄O₂Cl
- Мол. масса
- 394.85 г/моль
- SMILES
- CN(C)C(=O)CC1=NN(C2=CC=CC=C2)C(=O)C3=C1C4=C(C=C(C=C4)Cl)N3C
- Синонимы
- 2-(7-Chloro-5-methyl-4-oxo-3-phenyl-4,5-dihydro-3H-pyridazino[4,5-b]indol-1-yl)-N,N-dimethylacetamide; 3H-Pyridazino[4,5-b]indole-1-acetamide,7-chloro-4,5-dihydro-N,N,5-trimethyl-4-oxo-3-phenyl-; 7-chloro-4,5-dihydro-N,N,5-trimethyl-4-oxo-3-phenyl-3H-Pyridazino[4,5-b]indole-1-acetamide
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.