Биологическая активность
RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin связывание activity. The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the recognition specificity of the matrix proteins. RGD-4C is a αv-integrin лиганд, can conjugate with bioactive molecule to exert antitumor effects in animal models.
Оригинал на английском
RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin binding activity. The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the recognition specificity of the matrix proteins. RGD-4C is a αv-integrin ligand, can conjugate with bioactive molecule to exert antitumor effects in animal models.
Химические свойства
- CAS №
- 332179-76-7
- Брутто-формула
- C₄₂H₆₀N₁₄O₁₆S₄
- Мол. масса
- 1145.27 г/моль
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.