Биологическая активность
Ponsegromab (PF 06946860) is a мощный and селективный humanized anti-GDF15 моноклональный антитело with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the связывание of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers.
Оригинал на английском
Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 monoclonal antibody with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers.
Химические свойства
- CAS №
- 2368950-15-4 pH value: Corresponds to reference standard: PASS Non-reduced CE-SDS: >95% SEC-HPLC: >95% Isoelectric Point: Corresponds to reference standard Osmolality: Corresponds to reference standard: PASS Peptide mapping: Corresponds to reference standard: PASS N-terminal sequence: Corresponds to reference standard: PASS
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.