oestriol.

Биологическая активность

Estriol (also oestriol) is one of the three main estrogens produced by the human body. In pregnant women with multiple sclerosis (MS), estriol reduces the disease's symptoms noticeably, according to researchers at UCLA's Geffen Medical School. Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an антагонист when given in combination with estradiol. Estriol may play a role in the development of breast cancer, but based on in vitro research does appear to act as an антагонист to the G-protein coupled estrogen рецептор. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada. (Source: http://en.wikipedia.org/wiki/Estriol).