Биологическая активность
Precursor of MC1, is a vital component in the synthesis of MC1, a селективный and мощный COX-2 ингибитор. Radiolabeled MC1, [¹¹C]MC1, serves as a promising PET radioligand for imaging COX-2 expression in vivo. Its high selectivity, combined with its ability to non-invasively visualize COX-2 in disease states, makes it a valuable tool for research and clinical applications, particularly in neuroinflammation, cancer, and препарат development.
Оригинал на английском
Precursor of MC1, is a vital component in the synthesis of MC1, a selective and potent COX-2 inhibitor. Radiolabeled MC1, [¹¹C]MC1, serves as a promising PET radioligand for imaging COX-2 expression in vivo. Its high selectivity, combined with its ability to non-invasively visualize COX-2 in disease states, makes it a valuable tool for research and clinical applications, particularly in neuroinflammation, cancer, and drug development.
Химические свойства
- CAS №
- 1018480-97-1
- Брутто-формула
- C₁₆H₁₅N₃O₃S₂
- Мол. масса
- 361.44 г/моль
- SMILES
- C1(C2=CC=C(S(C)(=O)=O)C=C2)=NC(NCC2SC=CC=2)=CC(=O)N1
- Синонимы
- 2-(4-methanesulfonylphenyl)-6-{[(thiophen-2-yl)m ethyl]amino}pyrimidin-4-ol; 4(3H)-Pyrimidinone, 2-[4-(methylsulfonyl)phenyl]-6-[(2-thienylmethyl)amino]-; BDBM50373581; CHEMBL272393; PD166222 и ещё 4
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.