Биологическая активность
TCB-32 (Compound I-1) is a FGFR1 агонист with an EC50 of 0.88 μM. TCB-32 significantly increases клетка proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK 1/2 with excellent thermal stability. TCB-32 can replace bFGF in serum-free клетка culture media. TCB-32 can be used for tissue repair and wound healing related diseases like psoriasis and eczema research.
Оригинал на английском
TCB-32 (Compound I-1) is a FGFR1 agonist with an EC50 of 0.88 μM. TCB-32 significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK 1/2 with excellent thermal stability. TCB-32 can replace bFGF in serum-free cell culture media. TCB-32 can be used for tissue repair and wound healing related diseases like psoriasis and eczema research.
Химические свойства
- CAS №
- 352513-86-1
- Брутто-формула
- C₃₂H₄₀N₁₈O₂
- Мол. масса
- 708.78 г/моль
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.