Биологическая активность
EGFR-IN-32 is a мощный ингибитор of EGFR. Overexpression and mutation of the epidermal growth factor рецептор (EGFR) has been clearly demonstrated to lead to uncontrollable клетка growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-32 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185297A1, compound 2).
Оригинал на английском
EGFR-IN-32 is a potent inhibitor of EGFR. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been clearly demonstrated to lead to uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-32 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185297A1, compound 2).
Химические свойства
- CAS №
- 2701553-78-6
- Брутто-формула
- C₃₁H₃₄N₆O₃
- Мол. масса
- 538.64 г/моль
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.