Биологическая активность
DSPE-PEG-TCO (2000 Da) is a functionalized polyethylene glycol липид conjugate engineered to enhance препарат delivery systems. This amphiphilic polymer-липид hybrid demonstrates unique capabilities in optimizing the bioavailability and targeted distribution of hydrophobic therapeutic compounds. Its molecular architecture combines a липид anchor with a biocompatible PEG chain terminated by a trans-cyclooctene (TCO) group, enabling precise tissue-specific interactions while improving pharmacokinetic profiles. Researchers frequently employ this advanced biomaterial in developing nanoparticle formulations and лиганд-directed therapeutic platforms for enhanced precision medicine applications.
Оригинал на английском
DSPE-PEG-TCO (2000 Da) is a functionalized polyethylene glycol lipid conjugate engineered to enhance drug delivery systems. This amphiphilic polymer-lipid hybrid demonstrates unique capabilities in optimizing the bioavailability and targeted distribution of hydrophobic therapeutic compounds. Its molecular architecture combines a lipid anchor with a biocompatible PEG chain terminated by a trans-cyclooctene (TCO) group, enabling precise tissue-specific interactions while improving pharmacokinetic profiles. Researchers frequently employ this advanced biomaterial in developing nanoparticle formulations and ligand-directed therapeutic platforms for enhanced precision medicine applications.
Химические свойства
- SMILES
- CCCCCCCCCCCCCCCCCC(OC[C@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCOCCNC(OC1CCC/C=C/CC1)=O)=O)(O)=O)=O.[n]
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.