Биологическая активность
CVT-11127 functions as a мощный ингибитор of stearoyl-CoA desaturase (SCD), demonstrating significant биологическая активность. This compound triggers apoptotic pathways and effectively halts клетка cycle progression at the G1/S transition phase. Due to these mechanisms of action, CVT-11127 shows promise as a candidate for lung cancer research.
Оригинал на английском
CVT-11127 functions as a potent inhibitor of stearoyl-CoA desaturase (SCD), demonstrating significant biological activity. This compound triggers apoptotic pathways and effectively halts cell cycle progression at the G1/S transition phase. Due to these mechanisms of action, CVT-11127 shows promise as a candidate for lung cancer research.
Химические свойства
- CAS №
- 1018674-83-3
- Брутто-формула
- C₂₅H₂₃Cl₂N₅O₃
- Мол. масса
- 512.39 г/моль
- SMILES
- ClC1=C(Cl)C=CC(CNC2=NC3N(CCNC(=O)C)C(=O)C(C4C=CC(OC)=CC=4)=NC=3C=C2)=C1
- Синонимы
- N-[2-[6-[[(3,4-Dichlorophenyl)methyl]amino]-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetamide; N-[2-[6-[[(3,4-Dichlorophenyl)methyl]amino]-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]e; N-[2-(6-{[(3,4-dichloro-phenyl)methyl]amino}-2-(4-methoxyphenyl)-3-oxo-4-hydropyridino[2,3-b]pyrazin-4-yl)ethyl]acetamide; N-[2-[6-[[(3,4-Dichlorophenyl)Methyl]aMino]-2-(4-Methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetaMide; N-[2-[6-[[(3,4-Dichlorophenyl)methyl]amino]-2-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-4-yl]ethyl]acetamide
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 0°C (short term), -20°C (long term), desiccated
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.