Биологическая активность
Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and клетка cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.
Оригинал на английском
Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.
Химические свойства
- CAS №
- 61093-23-0
- Брутто-формула
- C₂₀H₂₄N₁₀O₁₄P₂
- Мол. масса
- 690.41 г/моль
- SMILES
- NC1=NC(=O)C2=C(N(C3OC4COP(OC5C(COP(OC4C3O)(O)=O)OC(N3C=NC4C(N=C(NC3=4)N)=O)C5O)(O)=O)C=N2)N1
- Синонимы
- CYCLIC DIGUANOSINE MONOPHOSPHATE ( C-DIGMP )3'-Guanylic acid,guanylyl-(3'®5')-,cyclic 3'®5'''-nucleotide; CYCLIC BIS ( 3' → 5' ) DIGUANYLIC ACID; 5'''-nucleotide; bis(3',5')-cyclic diguanylic acid
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C in DMS
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.