Биологическая активность
Almitrine Dimesylate (marketed as Duxil by Servier) is a diphenylmethylpiperazine derivative classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an агонист of peripheral chemoreceptors located on the carotid bodies. The препарат increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Оригинал на английском
Almitrine Dimesylate (marketed as Duxil by Servier) is a diphenylmethylpiperazine derivative classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Химические свойства
- CAS №
- 29608-49-9
- Брутто-формула
- C₂₈H₃₇F₂N₇O₆S₂
- Мол. масса
- 669.76 г/моль
- Синонимы
- Vectarion; Almitrin; Almitrina; Almitrinum; Almitrine.
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.