Биологическая активность
Oxfenicine, also known as UK-25842, is a carnitine palmitoyltransferase I (CPT-1) ингибитор involved in fatty acid metabolism in the heart. In animal studies oxfenicine acts as a cardioprotective agent during ischemia. Oxfenicine produces changes in myocardial substrate utilisation and is attributed to the protection of ischemic stressed myocardium by shifting the cardiac metabolism with reduction of FFA (Free Fatty Acid) utilisation. This may be favourable in circumstances with limited oxygen supply.
Оригинал на английском
Oxfenicine, also known as UK-25842, is a carnitine palmitoyltransferase I (CPT-1) inhibitor involved in fatty acid metabolism in the heart. In animal studies oxfenicine acts as a cardioprotective agent during ischemia. Oxfenicine produces changes in myocardial substrate utilisation and is attributed to the protection of ischemic stressed myocardium by shifting the cardiac metabolism with reduction of FFA (Free Fatty Acid) utilisation. This may be favourable in circumstances with limited oxygen supply.
Химические свойства
- CAS №
- 32462-30-9
- Брутто-формула
- C₈H₉NO₃
- Мол. масса
- 167.16 г/моль
- SMILES
- O=C(O)[C@@H](N)C1=CC=C(O)C=C1
- Синонимы
- UK-25,842; UK 25,842; UK25,842; UK-25842; UK 25842 и ещё 4
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.