Биологическая активность
Trimetazidine is a селективный long chain 3-ketoyl coenzyme A thiolase ингибитор with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective препарат, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) ингибитор.
Оригинал на английском
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective drug, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor.
Химические свойства
- CAS №
- 5011-34-7
- Брутто-формула
- C₁₄H₂₂N₂O₃
- Мол. масса
- 266.34 г/моль
Хранение и физические свойства
- Условия хранения
- Please store the product under the recommended conditions in the Certificate of Analysis.
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.