Биологическая активность
Tolazoline is a non-селективный competitive α-adrenergic рецептор антагонист. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with Sodium nitroprusside) successfully as an antidote to reverse the severe peripheral vasoconstriction which can occur as a result of overdose with certain 5-HT2A агонист drugs such as 25I-NBOMe, DOB and Bromodragonfly (prolonged severe vasoconstriction can lead to gangrene if untreated).
Оригинал на английском
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with Sodium nitroprusside) successfully as an antidote to reverse the severe peripheral vasoconstriction which can occur as a result of overdose with certain 5-HT2A agonist drugs such as 25I-NBOMe, DOB and Bromodragonfly (prolonged severe vasoconstriction can lead to gangrene if untreated).
Химические свойства
- CAS №
- 59-98-3
- Брутто-формула
- C₁₀H₁₂N₂
- Мол. масса
- 160.22 г/моль
- SMILES
- C1(CC2=CC=CC=C2)=NCCN1
- Синонимы
- Tolazoline, Benzalolin, Divascol, Pridazole, Priscol, Priscoline
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.