Биологическая активность
TH9402 is a dibrominated rhodamine derivative and мощный photosensitizer and useful in photodynamic therapy. TH9402 eradicates multiple myeloma (MM) and BC клетка lines, while sparing more than 50% of normal pluripotential blood stem cells from healthy volunteers. TH9402 offers an excellent potential as an ex vivo photodynamic purging agent for autologous transplantation in MM and BC treatment.
Оригинал на английском
TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential blood stem cells from healthy volunteers. TH9402 offers an excellent potential as an ex vivo photodynamic purging agent for autologous transplantation in MM and BC treatment.
Химические свойства
- CAS №
- 174230-05-8
- Брутто-формула
- C₂₁H₁₅Br₂ClN₂O₃
- Мол. масса
- 538.62 г/моль
- SMILES
- O=C(C1=CC=CC=C1C2=C3C=CC(N)=C(Br)C3=[O+]C4=C2C=CC(N)=C4Br)OC.[Cl-]
- Синонимы
- TH9402; TH-9402; TH 9402; Xanthylium.
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.