Биологическая активность
Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 μM). Reticulol was isolated from the culture broth of the strain Streptoverticillium sp. NA-4803. Recticulol (M.W. 222.2) exhibited a мощный in vitro cytotoxicity against A427, a human lung tumor клетка line, and B16F10, a mouse melanoma клетка line.
Оригинал на английском
Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 μM). Reticulol was isolated from the culture broth of the strain Streptoverticillium sp. NA-4803. Recticulol (M.W. 222.2) exhibited a potent in vitro cytotoxicity against A427, a human lung tumor cell line, and B16F10, a mouse melanoma cell line.
Химические свойства
- CAS №
- 26246-41-3
- Брутто-формула
- C₁₁H₁₀O₅
- Мол. масса
- 222.20 г/моль
- SMILES
- O=C1C2=C(O)C(OC)=C(O)C=C2C=C(C)O1
- Синонимы
- Reticulol; 6,8-dihydroxy-7-methoxy-3-methyl Isocoumarin, NSC 294978
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.