Биологическая активность
RO10-5824 is a D4-селективный partial агонист. RO10-5824 is a мощный candidate for the management of cocaine use disorders. The identification of effective medications for the management of cocaine use disorders remains an unmet public health challenge. In view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-селективный dopamine D1-4 рецептор antagonists.
Оригинал на английском
RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the management of cocaine use disorders. The identification of effective medications for the management of cocaine use disorders remains an unmet public health challenge. In view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-selective dopamine D1-4 receptor antagonists.
Химические свойства
- CAS №
- 189744-46-5
- Брутто-формула
- C₁₇H₂₀N₄
- Мол. масса
- 280.38 г/моль
- SMILES
- NC1=NC(C)=NC=C1CN2CC=C(C3=CC=CC=C3)CC2
- Синонимы
- RO10-5824; RO 10-5824; RO-10-5824; RO105824; RO 105824 и ещё 1
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.