Биологическая активность
Prasterone is an endogenous steroid hormone that acts as an агонист at ERβ, NMDA, and σ1 receptors, a partial агонист at ERα and AR, and антагонист at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working memory and cognition, inhibiting proliferation and migration of cervical cancer cells, increasing expression of various glutamate transporters to suppress seizures, and minimizing gastric acid secretion, липид peroxidation and ulcer formation.
Оригинал на английском
Prasterone is an endogenous steroid hormone that acts as an agonist at ERβ, NMDA, and σ1 receptors, a partial agonist at ERα and AR, and antagonist at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working memory and cognition, inhibiting proliferation and migration of cervical cancer cells, increasing expression of various glutamate transporters to suppress seizures, and minimizing gastric acid secretion, lipid peroxidation and ulcer formation.
Химические свойства
- CAS №
- 78590-17-7
- Брутто-формула
- C₁₉H₃₁NaO₇S
- Мол. масса
- 426.50 г/моль
- Синонимы
- 5-Androsten-3β-ol-17-one sulfate sodium salt dihydrate, Prasterone sulfate sodium salt dihydrate, Sodium dehydroepiandrosterone sulfate
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.