Биологическая активность
(+)-Pinoresinol is a lignan that diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an ингибитор of α-glucosidase and maltase. (+)-Pinoresinol scavenges ABTS but not 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in клетка-free assays. It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37 cells. (+)-Pinoresinol prevents клетка death induced by glutamate in HT22 cells and inhibits LPS-induced nitric oxide production in RAW 264.7 cells.
Оригинал на английском
(+)-Pinoresinol is a lignan that diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase. (+)-Pinoresinol scavenges ABTS but not 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in cell-free assays. It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37 cells. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells and inhibits LPS-induced nitric oxide production in RAW 264.7 cells.
Химические свойства
- Брутто-формула
- C₂₀H₂₂O₆
- Мол. масса
- 358.39 г/моль
- SMILES
- OC(C=C1)=C(OC)C=C1[C@@H]2[C@@]3([H])CO[C@H](C4=CC(OC)=C(O)C=C4)[C@@]3([H])CO2
- Синонимы
- (+)-Pinoresinol, NSC 35444
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.