Биологическая активность
Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test. Pentagastrin binds to the cholecystokinin-B рецептор, which is expressed widely in the brain. Activation of these receptors activates the phospholipase C second messenger system.
Оригинал на английском
Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test. Pentagastrin binds to the cholecystokinin-B receptor, which is expressed widely in the brain. Activation of these receptors activates the phospholipase C second messenger system.
Химические свойства
- CAS №
- 5534-95-2
- Брутто-формула
- C₃₇H₄₉N₇O₉S
- Мол. масса
- 767.89 г/моль
- SMILES
- CC(C)(C)OC(=O)NCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N
- Синонимы
- Pentagastrin; CHEMBL1328; ICI-50123; DSSTox_CID_28918; DSSTox_RID_83185 и ещё 7
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.