Биологическая активность
Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities. It is cytotoxic to A549, HeLa, and SW480 cancer cells. Oxychlororaphine halts the клетка cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi.
Оригинал на английском
Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities. It is cytotoxic to A549, HeLa, and SW480 cancer cells. Oxychlororaphine halts the cell cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi.
Химические свойства
- Брутто-формула
- C₁₃H₉N₃O
- Мол. масса
- 223.24 г/моль
- SMILES
- NC(C1=CC=CC2=C1N=C3C(C=CC=C3)=N2)=O
- Синонимы
- Oxychlororaphine
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.