Биологическая активность
Pranidipine, also known as OPC-13340 and FRC 8411, is a мощный and селективный calcium channel blocker potentially for the treatment of angina pectoris and hypertension. Pranidipine enhances nitric oxide-induced vascular relaxation. pranidipine prevents the left ventricular remodeling process accompanied by systolic and diastolic dysfunction, and inhibits abnormal cardiac gene expression after myocardial infarction.
Оригинал на английском
Pranidipine, also known as OPC-13340 and FRC 8411, is a potent and selective calcium channel blocker potentially for the treatment of angina pectoris and hypertension. Pranidipine enhances nitric oxide-induced vascular relaxation. pranidipine prevents the left ventricular remodeling process accompanied by systolic and diastolic dysfunction, and inhibits abnormal cardiac gene expression after myocardial infarction.
Химические свойства
- CAS №
- 99522-79-9
- Брутто-формула
- C₂₅H₂₄N₂O₆
- Мол. масса
- 448.48 г/моль
- SMILES
- O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OC/C=C/C3=CC=CC=C3
- Синонимы
- OPC-13340; OPC 13340; OPC13340; FRC 8411; FRC-8411 и ещё 2
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.