Биологическая активность
N-(acid-PEG3)-N-bis(PEG3-amine) is a PEG derivative containing two amino groups with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of антитело препарат conjugates.
Оригинал на английском
N-(acid-PEG3)-N-bis(PEG3-amine) is a PEG derivative containing two amino groups with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.
Химические свойства
- Брутто-формула
- C₂₅H₅₃N₃O₁₁
- Мол. масса
- 571.71 г/моль
- SMILES
- NCCOCCOCCOCCN(CCOCCOCCOCCC(O)=O)CCOCCOCCOCCN
- Синонимы
- N-(acid-PEG3)-N-bis(PEG3-amine)
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.