Биологическая активность
Mepolizumab (SB 240563) is a humanized моноклональный антитело that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma.
Оригинал на английском
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma.
Химические свойства
- CAS №
- 196078-29-2 pH value: Corresponds to reference standard： PASS Non-reduced CE-SDS: 98.3% SEC-HPLC: 99% Isoelectric Point: Corresponds to reference standard Bacterial Endotoxins Test: ＜1 EU/ml Exogenous Residual DNA: ＜1 pg/mg Residual protein A: ＜1 ng/mg Biological Activity: Compared with standard, the range ofbiological activity is 99% Osmolality: Corresponds to reference standard: PASS Peptide mapping: Corresponds to reference standard: PASS N-terminal sequence: Corresponds to reference standard:PASS
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.