Биологическая активность
Methotrimeprazine is a phenothiazine neuroleptic препарат. It is a low-potency antipsychotic (approximately half as мощный as chlorpromazine) with strong analgesic, hypnotic and antiemetic properties that is primarily used in palliative care. Serious side effects include tardive dyskinesia, akathisia, abnormalities in the electrical cycle of the heart, low blood pressure and the potentially fatal neuroleptic malignant syndrome. As is typical of phenothiazine antipsychotics, levomepromazine is a "dirty препарат", that is, it exerts its effects by blocking a variety of receptors, including adrenergic receptors, dopamine receptors, histamine receptors, muscarinic acetylcholine receptors and serotonin receptors. (Source: https://en.wikipedia.org/wiki/Levomepromazine).
Оригинал на английском
Methotrimeprazine is a phenothiazine neuroleptic drug. It is a low-potency antipsychotic (approximately half as potent as chlorpromazine) with strong analgesic, hypnotic and antiemetic properties that is primarily used in palliative care. Serious side effects include tardive dyskinesia, akathisia, abnormalities in the electrical cycle of the heart, low blood pressure and the potentially fatal neuroleptic malignant syndrome. As is typical of phenothiazine antipsychotics, levomepromazine is a "dirty drug", that is, it exerts its effects by blocking a variety of receptors, including adrenergic receptors, dopamine receptors, histamine receptors, muscarinic acetylcholine receptors and serotonin receptors. (Source: https://en.wikipedia.org/wiki/Levomepromazine).
Химические свойства
- CAS №
- 60-99-1
- Брутто-формула
- C₁₉H₂₄N₂Os
- Мол. масса
- 328.47 г/моль
- SMILES
- COC(C=C1N2C[C@H](C)CN(C)C)=CC=C1SC3=C2C=CC=C3
- Синонимы
- Levomepromazine; Nosinan; Nozinan; Levoprome.
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.