Биологическая активность
Lisofylline, also known as LSF, improves клеточный mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues. IL-12 and STAT-4 activation are important pathways linked to inflammation and autoimmune damage to insulin producing cells. Therefore, LSF and related analogs could provide a new therapeutic approach to prevent or reverse type 1 diabetes.
Оригинал на английском
Lisofylline, also known as LSF, improves cellular mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues. IL-12 and STAT-4 activation are important pathways linked to inflammation and autoimmune damage to insulin producing cells. Therefore, LSF and related analogs could provide a new therapeutic approach to prevent or reverse type 1 diabetes.
Химические свойства
- Брутто-формула
- C₁₃H₂₀N₄O₃
- Мол. масса
- 280.33 г/моль
- Синонимы
- LSF; Lisofylline; Lisofylline; CT 1501R; ProTec
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.