Биологическая активность
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to inactivated penicillin-связывание proteins (PBPs) located on the inner membrane of the bacterial клетка wall. PBPs, including transpeptidases, carboxypeptidases, and endopeptidases, participate in the terminal stages of assembling the bacterial клетка wall and in reshaping the клетка wall during growth and division. It is a prodrug and it has no antibacterial activity itself but quickly splits of acetone in the human body to form ampicillin, which is active against a variety of bacteria.
Оригинал на английском
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs, including transpeptidases, carboxypeptidases, and endopeptidases, participate in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. It is a prodrug and it has no antibacterial activity itself but quickly splits of acetone in the human body to form ampicillin, which is active against a variety of bacteria.
Химические свойства
- CAS №
- 3511-16-8
- Брутто-формула
- C₁₉H₂₃N₃O₄S
- Мол. масса
- 389.47 г/моль
- SMILES
- CC1(C(N2C(S1)C(C2=O)N3C(=O)C(NC3(C)C)C4=CC=CC=C4)C(=O)O)C
- Синонимы
- Hetacillin; Hetacilina; Hetacilline; Hetacillinum; Phenazacillin и ещё 1
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
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