Биологическая активность
GR-203040 is a селективный NK1 рецептор антагонист. GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR203040 is a novel anti-emetic agent, and the broad spectrum of anti-emetic activity, together with activity observed in three species, suggests that this compound is worthy of clinical investigation.
Оригинал на английском
GR-203040 is a selective NK1 receptor antagonist. GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR203040 is a novel anti-emetic agent, and the broad spectrum of anti-emetic activity, together with activity observed in three species, suggests that this compound is worthy of clinical investigation.
Химические свойства
- CAS №
- 168398-02-5
- Брутто-формула
- C₂₀H₂₆Cl₂N₆O
- Мол. масса
- 437.37 г/моль
- Синонимы
- GR-203040; GR 203040; GR203040; GR-203040 HCl; GR-203040 hydrochloride
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.