Биологическая активность
Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial агонист of the nicotinic acetylcholine рецептор. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle.
Оригинал на английском
Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle.
Химические свойства
- CAS №
- 541-22-0
- Брутто-формула
- C₁₆H₃₈Br₂N₂
- Мол. масса
- 418.30 г/моль
- SMILES
- C[N+](CCCCCCCCCC[N+](C)(C)C)(C)C.[Br-].[Br-]
- Синонимы
- Decamethonium; Decamethonum; Syncurine; DECAMETHONIUM ION; Lopac-D-1260 и ещё 1
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.