Биологическая активность
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a мощный, селективный factor Xa ингибитор, which has good oral bioavailability. Edoxaban is an anticoagulant препарат which acts as a direct factor Xa ингибитор. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non?–central-nervous-system systemic embolism.
Оригинал на английском
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non?–central-nervous-system systemic embolism.
Химические свойства
- Брутто-формула
- C₂₄H₃₀ClN₇O₄S
- Мол. масса
- 548.05 г/моль
- Синонимы
- DU-176; DU 176; DU176; DU176b; DU-176b и ещё 4
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.