Биологическая активность
липид 35 is an novel ионизируемый липид designed to enhance the delivery of mRNA to specific tissues, particularly the lungs.липид 35 demonstrates superior chemical stability, especially in storage conditions. This stability ensures that the липид maintains its integrity over extended periods, making it ideal for long-term storage and large-scale production.липид 35 exhibits high transfection efficiency in various клетка types, including nonimmune cells, endothelial cells, and epithelial cells. липид 35 has demonstrated excellent biocompatibility and safety in preclinical studies. It does not cause significant liver damage or adverse immune responses, making it a safer alternative for therapeutic applications.
Оригинал на английском
Lipid 35 is an novel ionizable lipid designed to enhance the delivery of mRNA to specific tissues, particularly the lungs.Lipid 35 demonstrates superior chemical stability, especially in storage conditions. This stability ensures that the lipid maintains its integrity over extended periods, making it ideal for long-term storage and large-scale production.Lipid 35 exhibits high transfection efficiency in various cell types, including nonimmune cells, endothelial cells, and epithelial cells. Lipid 35 has demonstrated excellent biocompatibility and safety in preclinical studies. It does not cause significant liver damage or adverse immune responses, making it a safer alternative for therapeutic applications.
Химические свойства
- Брутто-формула
- C₅₆H₁₁₂O₅N₄
- Мол. масса
- 921.53 г/моль
- SMILES
- CCCCCCCCC(CCCCCC)C(=O)OCCCCCCCCN(CCCCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCNC(=O)NCCCN(C)C
- Синонимы
- Lipid-35, Lipid35
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 1 года -20°C
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.