Биологическая активность
BAPTA is a селективный chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
Оригинал на английском
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
Химические свойства
- CAS №
- 85233-19-8
- Брутто-формула
- C₂₂H₂₄N₂O₁₀
- Мол. масса
- 476.43 г/моль
- SMILES
- O=C(CN(CC(O)=O)C1C(OCCOC2C(N(CC(O)=O)CC(O)=O)=CC=CC=2)=CC=CC=1)O
- Синонимы
- BAPTA; 1,2-Bis(2-aminophenoxy)-ethane-N,N,N'N'-tetraacetic acid; 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; 1,2-Bis-(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid; 2,2'-((2-(2-(3-(Bis(carboxymethyl)amino)phenoxy)-ethoxy)phenyl)azanediyl)diacetic acid и ещё 13
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Хранение и физические свойства
- Условия хранения
- 2 года -20°C порошок, 2 недели 4°C в ДМСО, 6 мес. -80°C в ДМСО
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.