Биологическая активность
JWH 081 is a cannabimimetic aminoalkylindole that shows a high-affinity for the central cannabinoid (CB1) рецептор with a Ki value of 1.2 nM and ten-fold reduced affinity for the peripheral cannabinoid (CB2) рецептор (Ki = 12.4 nM). JWH 081-N-(cyclohexylmethyl) analog is a synthetic CB where a cyclohexylmethyl group replaces the alkyl group of the parent compound. The physiological and toxicological properties of this compound are unknown.
Оригинал на английском
JWH 081 is a cannabimimetic aminoalkylindole that shows a high-affinity for the central cannabinoid (CB1) receptor with a Ki value of 1.2 nM and ten-fold reduced affinity for the peripheral cannabinoid (CB2) receptor (Ki = 12.4 nM). JWH 081-N-(cyclohexylmethyl) analog is a synthetic CB where a cyclohexylmethyl group replaces the alkyl group of the parent compound. The physiological and toxicological properties of this compound are unknown.
Химические свойства
- Брутто-формула
- C₂₇H₂₇NO₂
- Мол. масса
- 397.51 г/моль
- SMILES
- O=C(C1=CN(CC2CCCCC2)C3=C1C=CC=C3)C4=C5C=CC=CC5=C(OC)C=C4
- Синонимы
- CHM-081; CHM 081; CHM081
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.