Биологическая активность
Biotin-PEG4-alkyne is a PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the связывание to avidin molecules.
Оригинал на английском
Biotin-PEG4-alkyne is a PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
Химические свойства
- Брутто-формула
- C₂₁H₃₅N₃O₆S
- Мол. масса
- 457.59 г/моль
- SMILES
- O=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCOCCOCC#C)=O)[C@@]2([H])N1
- Синонимы
- Biotin-PEG4-alkyne
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
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