Биологическая активность
Biotin-PEG3-amineis PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the связывание to avidin molecules. PEG Linkers may be useful in the development of антитело препарат conjugates.
Оригинал на английском
Biotin-PEG3-amineis PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. PEG Linkers may be useful in the development of antibody drug conjugates.
Химические свойства
- Брутто-формула
- C₁₈H₃₄N₄O₅S
- Мол. масса
- 418.55 г/моль
- SMILES
- O=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCOCCN)=O)[C@@]2([H])N1
- Синонимы
- Biotin-PEG3-amine
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.