Биологическая активность
Bepafant, also known as WEB-2170 and STY-2108, is a platelet activating factor (PAF) антагонист potentially for the treatment of asthma. Bepafant triggered apoptosis in NB4, KG1, and NB4-MR4 cells where PTEN was expressed, but not in THP1 and U937 cells where PTEN was absent. Bepafant may produce significant anti-inflammatory effects.
Оригинал на английском
Bepafant, also known as WEB-2170 and STY-2108, is a platelet activating factor (PAF) antagonist potentially for the treatment of asthma. Bepafant triggered apoptosis in NB4, KG1, and NB4-MR4 cells where PTEN was expressed, but not in THP1 and U937 cells where PTEN was absent. Bepafant may produce significant anti-inflammatory effects.
Химические свойства
- CAS №
- 114776-28-2
- Брутто-формула
- C₂₃H₂₂ClN₅O₂S
- Мол. масса
- 467.97 г/моль
- Синонимы
- Bepafant; WEB-2170; WEB 2170; WEB2170; STY-2108 и ещё 2
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.