Биологическая активность
Ani9 is a мощный ANO1 ингибитор. Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. Ani9 may be a useful pharmacological tool for studying ANO1 and a potential development candidate for препарат therapy of cancer, hypertension, pain, diarrhea and asthma.
Оригинал на английском
Ani9 is a potent ANO1 inhibitor. Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. Ani9 may be a useful pharmacological tool for studying ANO1 and a potential development candidate for drug therapy of cancer, hypertension, pain, diarrhea and asthma.
Химические свойства
- Брутто-формула
- C₁₇H₁₇ClN₂O₃
- Мол. масса
- 332.78 г/моль
- SMILES
- O=C(N/N=C/C1=CC=CC=C1OC)COC2=CC=C(Cl)C=C2C
- Синонимы
- Ani9; Ani-9; Ani 9
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.