Биологическая активность
Aminothiadiazole, also known as NSC-4728; A-TDA; ADTA, is an inosine monophosphate dehydrogenase ингибитор potentially for the treatment of solid tumours. Aminothiadiazole is a synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of клетка proliferation and differentiation in a number of cells. This agent is also a селективный human adenosine A3 рецептор антагонист.
Оригинал на английском
Aminothiadiazole, also known as NSC-4728; A-TDA; ADTA, is an inosine monophosphate dehydrogenase inhibitor potentially for the treatment of solid tumours. Aminothiadiazole is a synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist.
Химические свойства
- CAS №
- 4005-51-0
- Брутто-формула
- C₂H₃N₃S
- Мол. масса
- 101.13 г/моль
- SMILES
- NC1=NN=CS1
- Синонимы
- Aminothiadiazole; NSC-4728; A-TDA; ADTA.
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.