Биологическая активность
Amino-Tri-(carboxyethoxymethyl)-methane is a PEG derivative containing an amino group with three terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of антитело препарат conjugates.
Оригинал на английском
Amino-Tri-(carboxyethoxymethyl)-methane is a PEG derivative containing an amino group with three terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.
Химические свойства
- Брутто-формула
- C₁₃H₂₃NO₉
- Мол. масса
- 337.33 г/моль
- SMILES
- NC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O
- Синонимы
- Amino-Tri-(carboxyethoxymethyl)-methane
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.