Биологическая активность
Amino-PEG8-t-Boc-hydrazide is a PEG derivative containing an amino group and a Boc-protected hydrazide. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups. PEG Linkers may be useful in the development of антитело препарат conjugates.
Оригинал на английском
Amino-PEG8-t-Boc-hydrazide is a PEG derivative containing an amino group and a Boc-protected hydrazide. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups. PEG Linkers may be useful in the development of antibody drug conjugates.
Химические свойства
- Брутто-формула
- C₂₄H₄₉N₃O₁₁
- Мол. масса
- 555.67 г/моль
- SMILES
- CC(C)(C)OC(NNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN)=O)=O
- Синонимы
- Amino-PEG8-t-Boc-hydrazide
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.