Биологическая активность
Amino-PEG25-acid is a PEG derivative containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of антитело препарат conjugates and препарат delivery methods.
Оригинал на английском
Amino-PEG25-acid is a PEG derivative containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
Химические свойства
- Брутто-формула
- C₅₃H₁₀₇NO₂₇
- Мол. масса
- 1190.42 г/моль
- Синонимы
- Amino-PEG25-acid
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.