Биологическая активность
Apronalide, also known as Allylisopropylacetylurea or Apronal, is a hypnotic/sedative препарат of the ureide (acylurea) group which may induce cytochrome P-450 through barbiturate-like activity. Though it is not a barbiturate, apronalide is similar in structure and action to the barbiturates, although considerably milder in comparison. Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use except in Japan.
Оригинал на английском
Apronalide, also known as Allylisopropylacetylurea or Apronal, is a hypnotic/sedative drug of the ureide (acylurea) group which may induce cytochrome P-450 through barbiturate-like activity. Though it is not a barbiturate, apronalide is similar in structure and action to the barbiturates, although considerably milder in comparison. Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use except in Japan.
Химические свойства
- Брутто-формула
- C₉H₁₆N₂O₂
- Мол. масса
- 184.24 г/моль
- SMILES
- C([C@@H](CC=C)C(C)C)(NC(N)=O)=O
- Синонимы
- Allylisopropylacetylurea, Apronal, Apronalide, Isodormid, Sedormid
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.