Биологическая активность
Aegeline is a main alkaloid isolated from Aegle marmelos Correa collected in Yogyakarta Indonesia. Aegeline inhibited the histamine release from RBL-2H3 cells induced by DNP(24)-BSA. Aegeline showed strong inhibition when RBL-2H3 cells induced by Ca(2+) stimulants such as thapsigargin and ionomycin. Tthe inhibitory effects of aegeline on the histamine release from mast cells depended on the type of mast клетка and also involved some mechanisms related to intracellular Ca(2+) signaling events via the same target of the action of thapsigargin or downstream process of intracellular Ca(2+) signaling in mast cells.
Оригинал на английском
Aegeline is a main alkaloid isolated from Aegle marmelos Correa collected in Yogyakarta Indonesia. Aegeline inhibited the histamine release from RBL-2H3 cells induced by DNP(24)-BSA. Aegeline showed strong inhibition when RBL-2H3 cells induced by Ca(2+) stimulants such as thapsigargin and ionomycin. Tthe inhibitory effects of aegeline on the histamine release from mast cells depended on the type of mast cell and also involved some mechanisms related to intracellular Ca(2+) signaling events via the same target of the action of thapsigargin or downstream process of intracellular Ca(2+) signaling in mast cells.
Химические свойства
- CAS №
- 456-12-2
- Брутто-формула
- C₁₈H₁₉NO₃
- Мол. масса
- 297.35 г/моль
- SMILES
- O=C(NCC(O)C1=CC=C(OC)C=C1)/C=C/C2=CC=CC=C2
- Синонимы
- Aegeline,
3D-структура молекулы
Вращайте мышью · Колесо — масштаб
Безопасность и документация
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