Биологическая активность
Patritumab deruxtecan (HER3-DXd) is an антитело-препарат conjugate (ADC) consisting of a fully human anti-HER3 IgG1 моноклональный антитело Patritumab (HY-P99275) attached to a topoisomerase I ингибитор payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity[1].
Оригинал на английском
Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab (HY-P99275) attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity[1].
Химические свойства
- CAS №
- 2227102-46-5 pH value: Corresponds to reference standard: PASS Non-reduced CE-SDS: >95% SEC-HPLC: >95% Isoelectric Point: Corresponds to reference standard Osmolality: Corresponds to reference standard: PASS Peptide mapping: Corresponds to reference standard: PASS N-terminal sequence: Corresponds to reference standard: PASS
Безопасность и документация
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