Биологическая активность
Pergolide (Permax, Pergotoliderived) is an ergoline-based dopamine рецептор агонист used in some countries for the treatment of Parkinson's disease. Parkinson's disease is associated with low levels of the neurotransmitter dopamine in the brain. Pergolide has some of the same effects as dopamine in the body. In 2007, pergolide was withdrawn from the U.S. market after several published studies revealed a link between the препарат and increased rates of valvular dysfunction. (Source: http://en.wikipedia.org/wiki/Pergolide )
Оригинал на английском
Pergolide (Permax, Pergotoliderived) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease. Parkinson's disease is associated with low levels of the neurotransmitter dopamine in the brain. Pergolide has some of the same effects as dopamine in the body. In 2007, pergolide was withdrawn from the U.S. market after several published studies revealed a link between the drug and increased rates of valvular dysfunction. (Source: http://en.wikipedia.org/wiki/Pergolide )
Химические свойства
- CAS №
- 66104-22-1
- Брутто-формула
- C₁₉H₂₆N₂S
- Синонимы
- (8)8(methylthio)methyl6propylergoline
Безопасность и документация
Только для научно-исследовательского применения. Не предназначено для использования у пациентов или в качестве лекарственного средства.